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IL17 Receptor B antibody (Alexa Fluor 647)
IL17RB
Reactivity: Mouse
FACS
Host: Rat
Monoclonal
9B10
Alexa Fluor 647
Product Details anti-IL17 Receptor B Antibody (Alexa Fluor 647)
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Target
See all IL17 Receptor B (IL17RB) Antibodies
IL17 Receptor B (IL17RB)
(Interleukin 17 Receptor B (IL17RB))
Reactivity
All reactivities for IL17 Receptor B antibodies
Mouse
Host
All hosts for IL17 Receptor B antibodies
Rat
Clonality
All clonalities for IL17 Receptor B antibodies
Monoclonal
Conjugate
All conjugates for IL17 Receptor B antibodies
This IL17 Receptor B antibody is conjugated to Alexa Fluor 647
Application
All applications for IL17 Receptor B antibodies
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
Clone
9B10
Isotype
IgG2a kappa
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Discover our top product IL17RB Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C
Target Details for IL17 Receptor B
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Target
IL17 Receptor B (IL17RB)
(Interleukin 17 Receptor B (IL17RB))
Alternative Name
IL-17RB (IL17RB Products )
Synonyms
IL17RB antibody, CRL4 antibody, EVI27 antibody, IL17BR antibody, IL17RH1 antibody, Evi27 antibody, IL-17ER antibody, IL-17Rh1 antibody, Il17br antibody, interleukin 17 receptor B antibody, IL17RB antibody, Il17rb antibody
Background
IL-17RB, also known as IL17RH1, belongs to the cytokine receptor family. IL-17RB possesses a unique intracellular signaling molecule called SEFIR, and is expressed similarily to fibroblast growth factor genes and IL-17R. It is reported to be expressed on iNKT cells, innate lymphoid cells (ILC), and Th2 cells. It binds IL-17B and IL-17E (IL-25) but not IL-17A or C. Its interaction with IL-25 has a higher affinity than that with IL-17B. Binding of IL-17RB and IL-25/IL-17E induces NF-kB mediated IL-8 production through interaction with TRAF6 and Act1. IL-17RB has been reported to play a role in autoimmune diseases such as rheumatoid arthritis and asthma.
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