GNLY antibody (Alexa Fluor 647)

Catalog No. ABIN2657203

Product Details anti-GNLY Antibody (Alexa Fluor 647)

Target: GNLY (Granulysin (GNLY))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GNLY antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

Clone: DH2

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for GNLY

Target: GNLY (Granulysin (GNLY))

Alternative Name: Granulysin (GNLY Products)

Synonyms: 519 antibody, D2S69E antibody, LAG-2 antibody, LAG2 antibody, NKG5 antibody, TLA519 antibody, granulysin antibody, GNLY antibody

Background: Granulysin is a member of the saposin-like protein family of lipid binding proteins (SAPLIP). It is expressed by NK cells and cytolytic T lymphocytes (CTL) as 9 kD and 15 kD forms. The 9 kD form is derived from the 15 kD form by cleavage at both amino- and carboxy-termini. Granulysin has broad cytolytic activities against a variety of tumor cells and microbes, including Gram-positive and -negative bacteria, fungi and parasites. It also functions as a chemoattractant for inflammatory cells and activates the cells expression of cytokines and chemokines.