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CD40 Ligand antibody (APC)
CD40LG
Reactivity: Mouse
WB, FACS
Host: Hamster
Monoclonal
MR1
APC
Product Details anti-CD40 Ligand Antibody (APC)
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Target
See all CD40 Ligand (CD40LG) Antibodies
CD40 Ligand (CD40LG)
Reactivity
All reactivities for CD40 Ligand antibodies
Mouse
Host
All hosts for CD40 Ligand antibodies
Hamster
Clonality
All clonalities for CD40 Ligand antibodies
Monoclonal
Conjugate
All conjugates for CD40 Ligand antibodies
This CD40 Ligand antibody is conjugated to APC
Application
All applications for CD40 Ligand antibodies
Western Blotting (WB), Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
Clone
MR1
Isotype
IgG
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Discover our top product CD40LG Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.2 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C
Target Details for CD40 Ligand
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Target
CD40 Ligand (CD40LG)
Alternative Name
CD154 (CD40LG Products )
Synonyms
CD154 antibody, cd40l antibody, CD40L antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TNFSF5 antibody, TRAP antibody, gp39 antibody, hCD40L antibody, CD40-L antibody, Cd40l antibody, Ly-62 antibody, Ly62 antibody, Tnfsf5 antibody, CD40 ligand antibody, TNF superfamily member 5 antibody, CD40LG antibody, cd40l antibody, Cd40lg antibody
Background
CD154 is a 39 kD TNF superfamily member also known as CD40 ligand, gp39, T-BAM, TRAP, and Ly-62. CD154 is an accessory molecule expressed predominantly on activated CD4+ lymphocytes that bind CD40. CD154 plays an important role in T-B cell costimulation. The MR1 antibody has been reported to inhibit the activation of T and B lymphocytes in vitro and antigen-specific lymphocyte responses in vivo.
Pathways
NF-kappaB Signaling , Production of Molecular Mediator of Immune Response , Cancer Immune Checkpoints
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