HSV ICP27 antibody

Catalog No. ABIN265584

Product Details anti-HSV ICP27 Antibody

Target: HSV ICP27 (Herpes Simplex Virus ICP27 (HSV ICP27))

Reactivity: Herpes Simplex Virus (HSV)

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSV ICP27 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Protein G agarose affinity chromatography

Clone: H1142

Isotype: IgG1 kappa

Application Details

Application Notes: Reactive with ICP27 of Herpes Simplex Virus in immunofluorescence (IFA) and western blot at 10 ug/ml.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/ml

Buffer: Phosphate Buffered Saline pH 7.4 (no azide)

Preservative: Azide free

Storage: -20 °C

References for anti-HSV ICP27 antibody (ABIN265584)

Tian, Devi-Rao, Golovanov, Sandri-Goldin: "The Interaction of the Cellular Export Adaptor Protein Aly/REF with ICP27 Contributes to the Efficiency of Herpes Simplex Virus 1 mRNA Export." in: Journal of virology, Vol. 87, Issue 13, pp. 7210-7, (2013) (PubMed).

Jin, Ma, Yan, Prabhakar, He: "Activation of NF-κB in CD8+ Dendritic Cells Ex Vivo by the γ134.5 Null Mutant Correlates with Immunity against Herpes Simplex Virus 1." in: Journal of virology, Vol. 86, Issue 2, pp. 1059-68, (2011) (PubMed).

Souki, Hernandez, Sandri-Goldin: "Arginine methylation of the RGG box does not appear to regulate ICP27 import during herpes simplex virus infection." in: Journal of virology, Vol. 85, Issue 13, pp. 6809-13, (2011) (PubMed).

Salaun, MacDonald, Larralde, Howard, Lochtie, Burgess, Brook, Malik, Gray, Graham: "Poly(A)-binding protein 1 partially relocalizes to the nucleus during herpes simplex virus type 1 infection in an ICP27-independent manner and does not inhibit virus replication." in: Journal of virology, Vol. 84, Issue 17, pp. 8539-48, (2010) (PubMed).

Johnson, Sandri-Goldin: "Efficient nuclear export of herpes simplex virus 1 transcripts requires both RNA binding by ICP27 and ICP27 interaction with TAP/NXF1." in: Journal of virology, Vol. 83, Issue 3, pp. 1184-92, (2009) (PubMed).

Johnson, Li, Sandri-Goldin: "The cellular RNA export receptor TAP/NXF1 is required for ICP27-mediated export of herpes simplex virus 1 RNA, but the TREX complex adaptor protein Aly/REF appears to be dispensable." in: Journal of virology, Vol. 83, Issue 13, pp. 6335-46, (2009) (PubMed).

Souki, Sandri-Goldin: "Arginine methylation of the ICP27 RGG box regulates the functional interactions of ICP27 with SRPK1 and Aly/REF during herpes simplex virus 1 infection." in: Journal of virology, Vol. 83, Issue 17, pp. 8970-5, (2009) (PubMed).

Su, Zhang, Wang, Fraser, Block: "Evidence that the immediate-early gene product ICP4 is necessary for the genome of the herpes simplex virus type 1 ICP4 deletion mutant strain d120 to circularize in infected cells." in: Journal of virology, Vol. 80, Issue 23, pp. 11589-97, (2006) (PubMed).

Hazrati, Galen, Lu, Wang, Ouyang, Keller, Lehrer, Herold: "Human alpha- and beta-defensins block multiple steps in herpes simplex virus infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 12, pp. 8658-66, (2006) (PubMed).

Target Details for HSV ICP27

Target: HSV ICP27 (Herpes Simplex Virus ICP27 (HSV ICP27))

Abstract: HSV ICP27 Products

Target Type: Viral Protein

Background: Mouse monoclonal antibody to ICP27 of Herpes Simplex Virus. This antibody originates from ascites fluids and is purified by protein G agarose affinity chromatography.