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HDAC10 antibody

HDAC10 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN265454
  • Target See all HDAC10 Antibodies
    HDAC10 (Histone Deacetylase 10 (HDAC10))
    Reactivity
    • 62
    • 31
    • 22
    • 4
    Human, Mouse, Rat
    Host
    • 53
    • 9
    Rabbit
    Clonality
    • 46
    • 16
    Polyclonal
    Conjugate
    • 28
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HDAC10 antibody is un-conjugated
    Application
    • 36
    • 28
    • 15
    • 14
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects endogenous levels of HDAC10 protein. (region surrounding Glu24)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product HDAC10 Primary Antibody
  • Application Notes
    ELISA: 1/5000-1/10000. Western blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    HDAC10 (Histone Deacetylase 10 (HDAC10))
    Alternative Name
    HDAC10 (HDAC10 Products)
    Synonyms
    HDAC10 antibody, wu:fd19e10 antibody, zgc:55652 antibody, MGC115178 antibody, histone deacetylase 10 antibody, HD10 antibody, AW548891 antibody, Hd10 antibody, histone deacetylase 10 antibody, histone deacetylase 10 L homeolog antibody, HDAC10 antibody, hdac10 antibody, hdac10.L antibody, hda10 antibody, Hdac10 antibody
    Background
    In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (for p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated mammalian RPD3) and HDAC3, all of which are related to the yeast transcriptional regulator Rpd3p, have been identified as histone deacetylases.Synonyms: HD10, Histone deacetylase 10
    Molecular Weight
    approx. 75 kDa
    Gene ID
    83933
    NCBI Accession
    NP_001152758
    UniProt
    Q969S8
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