SLC2A3
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Application Notes
ELISA: 1: 1000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
slc2a3 antibody, wu:fb92c06 antibody, zgc:92476 antibody, SLC2A3 antibody, GLUT3 antibody, AA408729 antibody, AL023014 antibody, AL024341 antibody, AU040424 antibody, C78366 antibody, Glut-3 antibody, Glut3 antibody, CEF-GT3 antibody, GLUT-3 antibody, SLC2A14 antibody, solute carrier family 2 (facilitated glucose transporter), member 3a antibody, solute carrier family 2 member 3 antibody, solute carrier family 2 (facilitated glucose transporter), member 3 antibody, solute carrier family 2 member 14 antibody, solute carrier family 2, facilitated glucose transporter member 3 antibody, slc2a3a antibody, SLC2A3 antibody, Slc2a3 antibody, SLC2A14 antibody, LOC100125981 antibody
Background
Glucose is the major source of our energy and there are numerous isoforms of the glucose transporter in mammals, including Glut1, Glut2, Glut3, Glut4, Glut5, Glut6, Glut7, Glut8 and Glut9. The Glut5 gene located on the short arm of human chromosome 1 encodes a 501-amino acid facilitative glucose transporter. Glut5 mRNA is highly expressed in small intestine and to a lesser extent in kidney, skeletal muscle and adipose tissue. Glut5 plays a critical role in fructose absorption in the small intestine and its expression is highly induced when exposed to a fructose-enriched diet. Glut5 transporter expressed in human skeletal muscle is specifically localized to the plasma membrane, where it participates in regulating hexose transfer across the sarcolemma. Glut8, a novel glucose transporter-like protein, exhibits significant sequence similarity with the other members of sugar transporter family. Glut8 comprises 12 putative membrane-spanning helices and several conserved motifs, which are important for transport activity. In human tissues, Glut8 is predominantly expressed in testis and, to a lesser extent, in most other tissues including skeletal muscle, heart, small intestine and brain.Synonyms: GLUT-3, Glucose transporter 3, Glucose transporter type 3 brain, Solute carrier family 2 facilitated glucose transporter member 3