Western Blot: 5 - 10 μg/mL. Immunoprecipitation. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Buffer
Phosphate buffered saline with 0.08 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
Target
SSRP1
(Structure Specific Recognition Protein 1 (SSRP1))
ATHMG antibody, NFD antibody, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR D antibody, SSRP1 antibody, high mobility group antibody, ssrp1 antibody, CG4817 antibody, Cf5 antibody, Dmel\\CG4817 antibody, DssRP antibody, SSRP antibody, dSSRP antibody, dSSRP1 antibody, dSsrp antibody, ssrp antibody, Ssrp1 antibody, DDBDRAFT_0188842 antibody, DDBDRAFT_0216434 antibody, DDB_0188842 antibody, DDB_0216434 antibody, wu:fa11b03 antibody, wu:fd10f06 antibody, FACT antibody, FACT80 antibody, T160 antibody, CIIDBP antibody, C81323 antibody, Hmg1-rs1 antibody, Hmgi-rs3 antibody, Hmgox antibody, high mobility group antibody, FACT complex subunit Ssrp1 antibody, FACT complex subunit SSRP1 antibody, Structure specific recognition protein antibody, structure specific recognition protein 1 antibody, transcription factor protein antibody, structure specific recognition protein 1a antibody, SSRP1 protein antibody, structure specific recognition protein 1 S homeolog antibody, HMG antibody, CpipJ_CPIJ002953 antibody, CpipJ_CPIJ020011 antibody, CMU_019430 antibody, Tsp_07406 antibody, LOC100286423 antibody, Ssrp antibody, ssrp1 antibody, SSRP1 antibody, ssrp1a antibody, nfd110 antibody, ssrp1.S antibody, Ssrp1 antibody
Background
SPT16 and SSRP1 are found in all eurkaryotic cells and exists as part of an essential heterodimer complex. Together, SPT16 and SSRP1 are a highly abundant nuclear complex that in mammals has been called FACT, or Facilitates Chromatin Transcription. FACT enhances the processivity of RNA polymerase II through nucleosomes. Evidence also points to a role for FACT in replication, possibly by enhancing DNA polymerase through nucleosomes as well.Synonyms: Chromatin-specific transcription elongation factor 80 kDa subunit, FACT 80 kDa subunit, FACT complex subunit SSRP1, FACTp80, Facilitates chromatin transcription complex subunit SSRP1, Recombination signal sequence recognition protein 1, Structure-specific recognition protein 1, T160