SUPT16H antibody (AA 321-640)

Catalog No. ABIN265054

Product Details anti-SUPT16H Antibody

Target: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Binding Specificity: AA 321-640

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUPT16H antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Specificity: This antibody reacts to FACT complex subunit SPT16.

Purification: Purified

Immunogen: Recombinant protein consisting of amino acids 321-640 of the human SPT16 protein conjugated to GST.

Isotype: IgG

Application Details

Application Notes: Western Blot: 5 - 10 μg/mL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Target Details for SUPT16H

Target: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Alternative Name: SUPT16H / FACT140 (SUPT16H Products)

Background: SPT16 and SSRP1 are found in all eurkaryotic cells and exists as part of an essential heterodimer complex. Together, SPT16 and SSRP1 are a highly abundant nuclear complex that in mammals has been called FACT, or Facilitates Chromatin Transcription. FACT enhances the processivity of RNA polymerase II through nucleosomes. Evidence also points to a role for FACT in replication, possibly by enhancing DNA polymerase through nucleosomes as well.Synonyms: Chromatin-specific transcription elongation factor 140 kDa subunit, FACT 140 kDa subunit, FACT complex subunit SPT16, FACTp140, Facilitates chromatin transcription complex subunit SPT16

Gene ID: 11198

NCBI Accession: NP_009123

UniProt: Q9Y5B9

Pathways: Chromatin Binding