RED1 antibody (AA 6-66)
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- Target See all RED1 (ADARB1) Antibodies
- RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))
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Binding Specificity
- AA 6-66
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Reactivity
- Rat
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Host
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Sheep
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Clonality
- Polyclonal
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Conjugate
- This RED1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Specificity
- This antibody recognizes ADAR2 (Adenosine Deaminase Acting on RNA 2).
- Purification
- Purified
- Immunogen
- GST fusion protein containing aa 6-66 of the rat RED1 coding sequence
- Isotype
- IgG
- Top Product
- Discover our top product ADARB1 Primary Antibody
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- Application Notes
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Western Blot: 1: 1000. POSITIVE CONTROL: Rat Brain.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons." in: EMBO molecular medicine, Vol. 5, Issue 11, pp. 1710-9, (2013) (PubMed).
: "Transduction of multiple effects of sphingosine 1-phosphate (S1P) on T cell functions by the S1P1 G protein-coupled receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 7, pp. 3500-7, (2003) (PubMed).
: "
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Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons." in: EMBO molecular medicine, Vol. 5, Issue 11, pp. 1710-9, (2013) (PubMed).
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- Target
- RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))
- Alternative Name
- ADARB1 / ADAR2 (ADARB1 Products)
- Background
- RED 1 also called ADAR2 is involved in the editing of the messenger RNAs for glutamate receptor (GluR) subunits by siteselective adenosine deamination. It edits both the GluR-B Q/R and R/G sites efficiently but converts the adenosine in hotspot1 much less efficiently.Synonyms: DRADA2, Double-stranded RNA-specific editase 1, RED1, RNA-editing deaminase 1, RNA-editing enzyme 1, dsRNA adenosine deaminase
- Molecular Weight
- 80.7 kDa
- Gene ID
- 25367
- NCBI Accession
- NP_001104525
- UniProt
- P51400
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