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IL12A antibody
IL12A
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IL12A Antibody
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Target
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IL12A
(Interleukin 12 alpha (IL12A))
Reactivity
All reactivities for IL12A antibodies
Human
Host
All hosts for IL12A antibodies
Rabbit
Clonality
All clonalities for IL12A antibodies
Polyclonal
Conjugate
All conjugates for IL12A antibodies
This IL12A antibody is un-conjugated
Application
All applications for IL12A antibodies
Western Blotting (WB), ELISA
Specificity
IL-12A antibody is human specific. IL-12A antibody will not cross-react with IL-12B.
Purification
IL-12A antibody is affinity chromatography purified via peptide column.
Immunogen
IL-12A antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IL-12A.
Isotype
IgG
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Discover our top product IL12A Primary Antibody
Alternatives
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Application Details
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Application Notes
IL-12A antibody can be used for detection of IL-12A by Western blot at 0.5 - 1 μ,g/mL.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
IL-12A antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C,4 °C
Storage Comment
IL-12A antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target Details for IL12A
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Target
IL12A
(Interleukin 12 alpha (IL12A))
Alternative Name
IL-12A (IL12A Products )
Synonyms
CLMF antibody, IL-12A antibody, NFSK antibody, NKSF1 antibody, P35 antibody, CLMF2 antibody, IL-12B antibody, NKSF antibody, NKSF2 antibody, p40 antibody, Il-12b antibody, Il12p40 antibody, Il-12p40 antibody, Il12 antibody, IL-12p40 antibody, IL-12p35 antibody, Il-12a antibody, Ll12a antibody, p35 antibody, IL12p35 antibody, Il-12 p35 antibody, IL12p40 antibody, IL12 antibody, IL-12 p35 antibody, interleukin 12A antibody, interleukin 12B antibody, interleukin 12b antibody, interleukin 12a antibody, Interleukin 12 level antibody, IL12A antibody, IL12B antibody, Il12b antibody, Il12a antibody, IL12 antibody, il12a antibody
Background
IL-12A is subunit of the cytokine IL-12 which acts on T- and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 35-kD subunit and a 40-kD subunit that is a member of the cytokine receptor family (1). IL-12 is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells (1,2). The responses of lymphocytes to IL-12 are mediated by the activator of transcription protein STAT4 (2). Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity (3).
Molecular Weight
Predicted: 22 kDa Observed: 22 kDa
Gene ID
3592
NCBI Accession
NP_000873
UniProt
P29459
Pathways
JAK-STAT Signaling , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Activated T Cell Proliferation
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