CILP antibody (AA 1051-1184) (Biotin)
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- Target See all CILP Antibodies
- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
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Binding Specificity
- AA 1051-1184
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CILP antibody is conjugated to Biotin
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- The immunogen falls within the Cartilage intermediate layer protein 1 C2 region.
- Cross-Reactivity
- Human, Rat
- Predicted Reactivity
- Mouse,Cow,Sheep,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CILP
- Isotype
- IgG
- Top Product
- Discover our top product CILP Primary Antibody
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anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 603-846) antibody
CILP Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 604-864) antibodyCILP Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 1051-1184) antibodyCILP Reactivity: Human, Rat WB, ELISA, FACS, ICC, IF (cc), IF (p), IHC (fro), IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (Internal Region) antibodyVerified CILP Reactivity: Rat WB, ELISA Host: Goat Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 129-226) antibodyCILP Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 129-226) antibodyCILP Reactivity: Human ELISA Host: Mouse Monoclonal 2D10 unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 129-226) antibodyCILP Reactivity: Human ELISA Host: Mouse Monoclonal 2C5 unconjugated
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
- Alternative Name
- CILP (CILP Products)
- Background
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Synonyms: CILP-1, HsT18872, Cartilage intermediate layer protein 1, Cartilage intermediate-layer protein, CILP, UNQ602/PRO1188
Background: Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage.
- Gene ID
- 8483
- UniProt
- O75339
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