DFNA5 antibody (AA 21-120)

Catalog No. ABIN2559452

Product Details anti-DFNA5 Antibody

Target: DFNA5 (Deafness, Autosomal Dominant 5 (DFNA5))

Binding Specificity: AA 21-120

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DFNA5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DFNA5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DFNA5

Target: DFNA5 (Deafness, Autosomal Dominant 5 (DFNA5))

Alternative Name: DFNA5 (DFNA5 Products)

Synonyms: Dfna5h antibody, fk59f08 antibody, zgc:91916 antibody, wu:fc41e05 antibody, wu:fk59f08 antibody, MGC83660 antibody, ICERE-1 antibody, 2310037D07Rik antibody, 4932441K13Rik antibody, EG14210 antibody, Fin15 antibody, gasdermin E antibody, gasdermin Eb antibody, DFNA5, deafness associated tumor suppressor antibody, gasdermin E L homeolog antibody, Gsdme antibody, gsdmeb antibody, DFNA5 antibody, gsdme.L antibody, GSDME antibody

Background:

Synonyms: ICERE-1, Non-syndromic hearing impairment protein 5, Inversely correlated with estrogen receptor expression 1, DFNA5, ICERE1

Background: Involved in apoptosis and cell survival. Plays a role in the TP53-regulated cellular response to DNA damage probably by cooperating with TP53.

Gene ID: 1687

UniProt: O60443

Pathways: Sensory Perception of Sound