TRPC7 antibody (AA 845-862) (Atto 488)
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- Target See all TRPC7 Antibodies
- TRPC7 (Transient Receptor Potential Cation Channel, Subfamily C, Member 7 (TRPC7))
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Binding Specificity
- AA 845-862
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TRPC7 antibody is conjugated to Atto 488
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Antibody Array (AA)
- Specificity
- Detects ~100 kDa.
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Protein G Purified
- Immunogen
- Synthetic peptide amino acids 845-862 of human TRPC7
- Clone
- N64A-36 (Formerly S64A-36)
- Isotype
- IgG1
- Top Product
- Discover our top product TRPC7 Primary Antibody
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- Application Notes
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- WB (1:1000)
- IHC (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Comment
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1 μg/ml of ABIN2485420 was sufficient for detection of TrpC7 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Conjugated antibodies should be stored at 4°C
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- Target
- TRPC7 (Transient Receptor Potential Cation Channel, Subfamily C, Member 7 (TRPC7))
- Alternative Name
- TRPC7 (TRPC7 Products)
- Synonyms
- TRP7 antibody, TRP-7 antibody, Trrp8 antibody, TRPC7 antibody, TRPM2 antibody, transient receptor potential cation channel subfamily C member 7 antibody, transient receptor potential cation channel, subfamily C, member 7 antibody, short transient receptor potential channel 7 antibody, TRPC7 antibody, Trpc7 antibody, LOC100012798 antibody
- Background
- Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a non-selective cation channel that is directly activated by DAG. TrpC7 shows constitutive activity and susceptibility to negative regulation by extracellular Ca2+. Because of this, TrpC7 plays an important role in the Ca2+ signaling pathway (1). TrpC7 is also expressed abundantly in the heart, and combined with its ability to act as a Ca2+ channel, TrpC7 might contribute to the process of heart failure (2).
- Gene ID
- 57113
- NCBI Accession
- NP_065122
- UniProt
- Q9HCX4
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