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ADRA2C antibody (AA 442-462) (Biotin)

ADRA2C Reactivity: Human WB, ICC, IF Host: Mouse Monoclonal S330A-80 Biotin
Catalog No. ABIN2485208
  • Target See all ADRA2C Antibodies
    ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))
    Binding Specificity
    • 24
    • 22
    • 16
    • 10
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 442-462
    Reactivity
    • 82
    • 47
    • 20
    • 7
    • 4
    • 4
    • 2
    • 1
    Human
    Host
    • 60
    • 25
    Mouse
    Clonality
    • 60
    • 25
    Monoclonal
    Conjugate
    • 32
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADRA2C antibody is conjugated to Biotin
    Application
    • 55
    • 25
    • 20
    • 17
    • 14
    • 13
    • 13
    • 13
    • 12
    • 11
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    Detects 50 kDa or larger (possibly due to dimerization). Does not cross-react with other adrenergic receptors.
    Cross-Reactivity
    Human, Mouse
    Purification
    Protein G Purified
    Immunogen
    Synthetic peptide amino acids 442- 462 (QDFRRSFKHILFRRRRRGFRQ, cytoplasmic C-terminus) of human Alpha-2C adrenergic receptor
    Clone
    S330A-80
    Isotype
    IgG1
    Top Product
    Discover our top product ADRA2C Primary Antibody
  • Application Notes
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Comment

    1 μg/ml of ABIN2485208 was sufficient for detection of Alpha2C Adrenergic Receptor in 20 μg of COS cells transiently transfected with HA-tagged Alpha- lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))
    Alternative Name
    Alpha2C Adrenergic (ADRA2C Products)
    Synonyms
    ADRA2L2 antibody, ADRA2RL2 antibody, ADRARL2 antibody, ALPHA2CAR antibody, Adra-2c antibody, [a]2C antibody, alpha2-C4 antibody, alpha2C antibody, zgc:194523 antibody, zgc:194541 antibody, adra2c antibody, ADRA2B antibody, ADRA2C antibody, adrenoceptor alpha 2C antibody, adrenergic receptor, alpha 2c antibody, ADRA2C antibody, Adra2c antibody, adra2c antibody
    Background
    The alpha 2C Adrenergic Receptor controls the release of neurotransmitter from central adrenergic neurons and from sympathetic nerves in the heart. This receptor also plays a role in cognitive and behavioral function. Two variants are produced by alternative splicing. Alpha 2C Adrenergic Receptor has been reported extensively in the brain. Blood, corpus cavermosum, kidney, and heart tissues have also been reported to express the protein.
    Gene ID
    152
    NCBI Accession
    NP_000674
    UniProt
    P18825
    Pathways
    EGFR Signaling Pathway, cAMP Metabolic Process
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