CACNB2 antibody (AA 189-205) (APC)
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- Target See all CACNB2 Antibodies
- CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))
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Binding Specificity
- AA 189-205
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Reactivity
- Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CACNB2 antibody is conjugated to APC
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Antibody Array (AA)
- Specificity
- Detects ~78 kDa. No cross reactivity against Cavβ1, Cavβ3, Cavβ4.
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Protein G Purified
- Immunogen
- Synthetic peptide amino acids 189-205 of rat CavBeta2
- Clone
- N8b-1 (Formerly S8B-1)
- Isotype
- IgG1
- Top Product
- Discover our top product CACNB2 Primary Antibody
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- Application Notes
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- WB (1:1000)
- IHC (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Comment
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1 μg/ml of ABIN2485037 was sufficient for detection of Cavβ2 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Conjugated antibodies should be stored at 4°C
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- Target
- CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))
- Alternative Name
- CavBeta2 (CACNB2 Products)
- Synonyms
- CACNLB2 antibody, CAVB2 antibody, MYSB antibody, AW060387 antibody, CAB2 antibody, Cavbeta2 antibody, Cchb2 antibody, Cacnlb2 antibody, Cacnb2 antibody, CACNB2 antibody, CACNB2.2 antibody, cacnb2a antibody, im:7141271 antibody, si:dkey-32m20.2 antibody, calcium voltage-gated channel auxiliary subunit beta 2 antibody, calcium channel, voltage-dependent, beta 2 subunit antibody, calcium channel, voltage-dependent, beta 2b antibody, CACNB2 antibody, Cacnb2 antibody, cacnb2b antibody
- Background
- Cav Beat subunits are involved in the transport of the pore forming alpha1 subunit to the plasma membrane (1). They also shield an ER Retention signal on the alpha1 subunit, thereby guiding the pore-forming subunit to the target membrane (2, 3). They also determine the biophysical properties of the calcium channel (3).
- Gene ID
- 116600
- NCBI Accession
- NP_446303
- UniProt
- Q8VGC3
- Pathways
- Skeletal Muscle Fiber Development
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