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Bassoon antibody (AA 786-1041) (APC)

BSN Reactivity: Human IHC, WB Host: Rabbit Polyclonal APC
Catalog No. ABIN2484541
  • Target See all Bassoon (BSN) Antibodies
    Bassoon (BSN)
    Binding Specificity
    • 12
    • 2
    • 2
    • 1
    AA 786-1041
    Reactivity
    • 24
    • 14
    • 14
    • 1
    • 1
    Human
    Host
    • 24
    • 3
    Rabbit
    Clonality
    • 24
    • 3
    Polyclonal
    Conjugate
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Bassoon antibody is conjugated to APC
    Application
    • 19
    • 17
    • 4
    • 4
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    Specificity
    Detects ~420 kDa. Multiple isoforms can be detected.
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Protein A Purified
    Immunogen
    NM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein
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    Discover our top product BSN Primary Antibody
  • Application Notes
    • WB (1:1000)
    • IHC (1:400)
    • optimal dilutions for assays should be determined by the user.
    Comment

    1 μg/ml of ABIN2484541 was sufficient for detection of Bassoon in 10 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat ant rabbit IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    Bassoon (BSN)
    Alternative Name
    Bassoon (BSN Products)
    Synonyms
    Znf231 antibody, ZNF231 antibody, bassoon antibody, bassoon (presynaptic cytomatrix protein) antibody, bassoon presynaptic cytomatrix protein antibody, Bsn antibody, BSN antibody
    Background
    Bassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntington, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to co-localize with GABA (A) and glutamate (GluR1) receptors (1).
    Gene ID
    8927
    NCBI Accession
    NP_003449
    UniProt
    Q9UPA5
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