CDC37 antibody (Atto 488)

Catalog No. ABIN2484516

Product Details anti-CDC37 Antibody (Atto 488)

Target: CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC37 antibody is conjugated to Atto 488

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Detects ~44.5 kDa.

Cross-Reactivity: Human

Purification: Protein A Purified

Immunogen: Native human Cdc37, full length

Application Details

Application Notes:

• WB (1:2000)
• ICC/IF (1:200)
• optimal dilutions for assays should be determined by the user.

Comment:

A 1:2000 dilution of ABIN2484516 was sufficient for detection of cdc37 in 20 μg of HeLa cell lysate by ECL immunoblot analysis.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.68 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Conjugated antibodies should be stored at 4°C

Target Details for CDC37

Target: CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))

Alternative Name: CDC37 (CDC37 Products)

Synonyms: CG12019 antibody, CPDR-1 antibody, CPDR-2 antibody, DROCPDR antibody, Dmel\\CG12019 antibody, E(sev)3B antibody, cdc37 antibody, Afu4g10010 antibody, P50CDC37 antibody, p50 antibody, p50Cdc37 antibody, CG12019 gene product from transcript CG12019-RA antibody, cell division cycle 37 homolog antibody, Hsp90 co-chaperone Cdc37 antibody, Cdc37p antibody, cell division cycle 37 antibody, Cdc37 antibody, cdc37 antibody, AFUA_4G10010 antibody, CDC37 antibody

Background: HSP90 co-chaperone Cdc37 is a protein that is encoded by the CDC37 gene. It has been found to form complexes with HSP90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK and elF-2 alpha kinases. It is thought to play a critical role in directing HSP90 to its target kinases (1, 2). CDC37 is necessary for maintaining prostate tumor cell growth and represents a novel target in the exploration for multi-targeted therapies (3, 4).

Gene ID: 11140

NCBI Accession: NP_008996

UniProt: Q16543