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SERPINH1 antibody (HRP)

SERPINH1 Reactivity: Human WB, IF, ICC Host: Mouse Monoclonal 1C4-1A6 HRP
Catalog No. ABIN2484374
  • Target See all SERPINH1 Antibodies
    SERPINH1 (Serpin Family H Member 1 (SERPINH1))
    Reactivity
    • 64
    • 25
    • 25
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 48
    • 27
    Mouse
    Clonality
    • 48
    • 27
    Monoclonal
    Conjugate
    • 40
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SERPINH1 antibody is conjugated to HRP
    Application
    • 56
    • 30
    • 24
    • 21
    • 15
    • 8
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Detects 47 kDa.
    Cross-Reactivity
    Human
    Purification
    Protein G Purified
    Immunogen
    Human HSP47, full length
    Clone
    1C4-1A6
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product SERPINH1 Primary Antibody
  • Application Notes
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Comment

    1 μg/ml of ABIN2484374 was sufficient for detection of HSP47 in 20 μg of heat shocked HeLa cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    SERPINH1 (Serpin Family H Member 1 (SERPINH1))
    Alternative Name
    HSP47 (SERPINH1 Products)
    Background
    HSP47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of HSP47 around fibrotic lesions (1). The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since HSP47 binds a single substrate (2). Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils (3).
    Gene ID
    871
    NCBI Accession
    NP_001193943
    UniProt
    P50454
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