MDC1 antibody (N-Term) (FITC)
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- Target See all MDC1 Antibodies
- MDC1 (Mdc1 (MDC1))
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Binding Specificity
- N-Term
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Reactivity
- Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This MDC1 antibody is conjugated to FITC
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Detects ~184 kDa. This antibody recognizes MDC1 at and around the N-terminus.
- Cross-Reactivity
- Chimpanzee, Cow, Human, Mouse
- Purification
- Protein G Purified
- Immunogen
- GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus
- Clone
- P2B11
- Isotype
- IgG1
- Top Product
- Discover our top product MDC1 Primary Antibody
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- Application Notes
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- WB (1:2000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Comment
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0.5 μg/ml of ABIN2484152 was sufficient for detection of MDC1 in 10 μg of HeLa cell lysate by ECL immunoblot analysis.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Conjugated antibodies should be stored at 4°C
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- Target
- MDC1 (Mdc1 (MDC1))
- Alternative Name
- MDC1 (MDC1 Products)
- Synonyms
- 6820401C03 antibody, AA413496 antibody, Nfbd1 antibody, mKIAA0170 antibody, NFBD1 antibody, mediator of DNA damage checkpoint 1 antibody, mediator of DNA-damage checkpoint 1 antibody, Mdc1 antibody, MDC1 antibody
- Background
- MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.
- Gene ID
- 240087
- NCBI Accession
- NP_001010833
- UniProt
- Q5PSV9
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