DUX4 antibody (C-Term) (Atto 488)
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- Target See all DUX4 Antibodies
- DUX4 (Double Homeobox 4 (DUX4))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This DUX4 antibody is conjugated to Atto 488
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Detects ~45 kDa. No cross-reactivity with DUX4c.
- Cross-Reactivity
- Human, Mouse
- Purification
- Protein G Purified
- Immunogen
- C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (gst) tag
- Clone
- P2B1
- Isotype
- IgG1
- Top Product
- Discover our top product DUX4 Primary Antibody
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anti-Double Homeobox 4 (DUX4) (AA 246-275) antibody
DUX4 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB29833 unconjugated
anti-Double Homeobox 4 (DUX4) (C-Term) antibodyDUX4 Reactivity: Human WB, IHC, IF, ICC Host: Mouse Monoclonal P2B1 unconjugated
anti-Double Homeobox 4 (DUX4) (AA 217-402) antibodyDUX4 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Double Homeobox 4 (DUX4) (AA 376-404), (C-Term) antibodyDUX4 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB32790 unconjugated
anti-Double Homeobox 4 (DUX4) (C-Term) antibody (HRP)DUX4 Reactivity: Human WB, IHC, IF, ICC Host: Mouse Monoclonal P2B1 HRP
anti-Double Homeobox 4 (DUX4) (C-Term) antibody (FITC)DUX4 Reactivity: Human WB, IHC, IF, ICC Host: Mouse Monoclonal P2B1 FITC
anti-Double Homeobox 4 (DUX4) (C-Term) antibody (Biotin)DUX4 Reactivity: Human WB, IHC, IF, ICC Host: Mouse Monoclonal P2B1 Biotin
anti-Double Homeobox 4 (DUX4) (C-Term) antibody (PE)DUX4 Reactivity: Human WB, IHC, IF, ICC Host: Mouse Monoclonal P2B1 PE
anti-Double Homeobox 4 (DUX4) (C-Term) antibody (APC)DUX4 Reactivity: Human WB, IHC, IF, ICC Host: Mouse Monoclonal P2B1 APC
anti-Double Homeobox 4 (DUX4) (C-Term) antibody (PerCP)DUX4 Reactivity: Human WB, IHC, IF, ICC Host: Mouse Monoclonal P2B1 PerCP
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- Application Notes
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- WB (1:1000)
- ICC/IF (1:1000)
- optimal dilutions for assays should be determined by the user.
- Comment
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1 μg/ml of ABIN2482287 was sufficient for detection of DUX4 in 20 μg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG: HRP as teh secondary.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Conjugated antibodies should be stored at 4°C
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- Target
- DUX4 (Double Homeobox 4 (DUX4))
- Alternative Name
- DUX4 (DUX4 Products)
- Synonyms
- DUX4 antibody, DUX4L antibody, double homeobox, 4 antibody, double homeobox 4 antibody, DUX4 antibody
- Background
- DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1 (1). Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4). In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues (5).
- Gene ID
- 22947
- NCBI Accession
- NP_149418
- UniProt
- F5GZ66
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