2B4 antibody

Catalog No. ABIN2479426

Product Details anti-2B4 Antibody

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This 2B4 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Characteristics: Purified IgG

Purification: Purified

Clone: 2B4-69

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-2B4 antibody (ABIN2479426)

Bengsch, Martin, Thimme: "Restoration of HBV-specific CD8+ T cell function by PD-1 blockade in inactive carrier patients is linked to T cell differentiation." in: Journal of hepatology, Vol. 61, Issue 6, pp. 1212-9, (2014) (PubMed).

Raziorrouh, Schraut, Gerlach, Nowack, Grüner, Ulsenheimer, Zachoval, Wächtler, Spannagl, Haas, Diepolder, Jung: "The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8+ T-cell function." in: Hepatology (Baltimore, Md.), Vol. 52, Issue 6, pp. 1934-47, (2010) (PubMed).

Romero, Zapater, Calvo, Kalko, de la Fuente, Tovar, Ockeloen, Pizcueta, Engel: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).

Target Details for 2B4

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Alternative Name: CD244 (CD244 Products)

Gene ID: 51744

UniProt: Q9BZW8