PIK3R2 antibody (Subunit beta)

Catalog No. ABIN2476135

Product Details anti-PIK3R2 Antibody

Target: PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

Binding Specificity: Subunit beta

Reactivity: Human, Cow, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This PIK3R2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Monkey

Characteristics: Purified IgG

Purification: Purified

Immunogen: Balculovirus expressed (Recombinant) p85 beta subunit of bovine PI-3 kinase.

Clone: T15

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-PIK3R2 antibody (ABIN2476135)

Brehme, Hantschel, Colinge, Kaupe, Planyavsky, Köcher, Mechtler, Bennett, Superti-Furga: "Charting the molecular network of the drug target Bcr-Abl." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 18, pp. 7414-9, (2009) (PubMed).

Hale, Batty, Downes, Randall: "Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85 suggests a novel mechanism for phosphoinositide 3-kinase activation." in: The Journal of biological chemistry, Vol. 283, Issue 3, pp. 1372-80, (2008) (PubMed).

Ehrhardt, Wolff, Pleschka, Planz, Beermann, Bode, Schmolke, Ludwig: "Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses." in: Journal of virology, Vol. 81, Issue 7, pp. 3058-67, (2007) (PubMed).

Target Details for PIK3R2

Target: PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

Alternative Name: pi-3 KINASE p85 SUBUNIT beta (PI3K p85b Products)

Synonyms: MPPH antibody, P85B antibody, p85 antibody, p85-BETA antibody, pik3r2 antibody, MGC80449 antibody, p85beta antibody, phosphoinositide-3-kinase regulatory subunit 2 antibody, phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta) antibody, phosphoinositide-3-kinase, regulatory subunit 2 (beta) antibody, PIK3R2 antibody, pik3r2 antibody, Pik3r2 antibody

Gene ID: 5296, 18709, 29741

UniProt: O00459, O08908, P23726, Q63788

Pathways: VEGF Signaling, BCR Signaling