FCAR antibody

Catalog No. ABIN2472754

Product Details anti-FCAR Antibody

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FCAR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP)

Characteristics: Purified IgG

Purification: Purified

Immunogen: Recombinant soluble human Fc alpha R

Clone: MIP8a

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-FCAR antibody (ABIN2472754)

Lu, Marjon, Marnell, Wang, Mold, Du Clos, Sun: "Recognition and functional activation of the human IgA receptor (FcalphaRI) by C-reactive protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 12, pp. 4974-9, (2011) (PubMed).

Duc, Johansen, Corthésy: "Antigen binding to secretory immunoglobulin A results in decreased sensitivity to intestinal proteases and increased binding to cellular Fc receptors." in: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 953-60, (2010) (PubMed).

Zhang, Bi, Oldroyd, Lachmann: "Neutrophil lactoferrin release induced by IgA immune complexes differed from that induced by cross-linking of fcalpha receptors (FcalphaR) with a monoclonal antibody, MIP8a." in: Clinical and experimental immunology, Vol. 121, Issue 1, pp. 106-11, (2000) (PubMed).

Target Details for FCAR

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Alternative Name: CD89 (FCAR Products)

Background: Synonyms: Fc ALPHA R

Gene ID: 2204

UniProt: P24071