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MST1R antibody (Internal Region)
MST1R
Reactivity: Human, Gibbon
ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MST1R Antibody
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Target
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MST1R
(Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
Binding Specificity
All epitopes for MST1R antibodies
Internal Region
Reactivity
All reactivities for MST1R antibodies
Human, Gibbon
Host
All hosts for MST1R antibodies
Rabbit
Clonality
All clonalities for MST1R antibodies
Polyclonal
Conjugate
All conjugates for MST1R antibodies
This MST1R antibody is un-conjugated
Application
All applications for MST1R antibodies
ELISA, Immunohistochemistry (IHC)
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins, except FANCE (50 % ).
Purification
Immunoaffinity Chromatography
Immunogen
MST1R antibody was raised against a peptide located near the internal domain of MST1R (Human).
Top Product
Discover our top product MST1R Primary Antibody
Alternatives
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anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (pTyr1238), (pTyr1239) antibody
MST1R
Reactivity: Human, Mouse, Rat
WB, ELISA, IHC (p), FACS, ICC, IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
MST1R antibody can be used in immunohistochemistry starting at 20 μg/mL.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS, 0.1 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
As with all antibodies avoid freeze/thaw cycles.
Storage
4 °C/-80 °C
Storage Comment
MST1R antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
Target Details for MST1R
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Target
MST1R
(Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
Alternative Name
MST1R (MST1R Products )
Synonyms
CD136 antibody, CDw136 antibody, PTK8 antibody, RON antibody, Fv-2 antibody, Fv2 antibody, Ron antibody, STK antibody, Cdw136 antibody, Ptk8 antibody, Stk antibody, macrophage stimulating 1 receptor antibody, macrophage stimulating 1 receptor (c-met-related tyrosine kinase) antibody, MST1R antibody, Mst1r antibody
Background
MST1R/Ron, a HGF Receptor/MET-type protein kinase, mediates the biological activities of macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival. The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding results in tyrosine phosphorylation of the beta chain. In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period. The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers.
Gene ID
4486
UniProt
Q04912
Pathways
RTK Signaling
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