DDR1
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
2G4E12
unconjugated
Application Notes
DDR1 antibody can be used in ELISA, Western Blot starting at 1 - 2 μg/mL, immunocytochemistry, immunohistochemistry starting at 10 μg/mL, immunoprecipitation starting at 1 - 2 μg/mL, and flow cytometry.
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, 0.1 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
As with all antibodies avoid freeze/thaw cycles.
Storage
4 °C/-80 °C
Storage Comment
DDR1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
DDR1 is a DDR/TKT type protein kinase. DDR1 is activated by various types of collagen, including types I through IV. Binding of collagen to DDR1 protein results in autophosphorylation and a delayed but sustained tyrosine kinase activation. DDR1 may function in cell-to-cell interaction or recognition. At least three mRNA variants, resulting in different protein isoforms of 875, 913 and 919 amino acids, have been reported. DDR1 protein has been shown to be over expressed in human breast, ovarian, esophageal and pediatric brain tumors.