CasLTR2 antibody (1st Extracellular Domain)

Catalog No. ABIN2469296

Product Details anti-CasLTR2 Antibody

Target: CasLTR2 (CYSLTR2) (Cysteinyl Leukotriene Receptor 2 (CYSLTR2))

Binding Specificity: 1st Extracellular Domain

Reactivity: Human, Horse, Gibbon

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CasLTR2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR109B (59 % ), OXGR1 (59 %), GPR81 (59 %).

Purification: Immunoaffinity Chromatography

Immunogen: CYSLTR2 antibody was raised against a peptide located in the 1st extracellular domain of CYSLTR2 (Human).

Application Details

Application Notes: CYSLTR2 antibody can be used in immunohistochemistry starting at 13 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: CYSLTR2 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for CasLTR2

Target: CasLTR2 (CYSLTR2) (Cysteinyl Leukotriene Receptor 2 (CYSLTR2))

Alternative Name: CYSLTR2 (CYSLTR2 Products)

Synonyms: CYSLTR2 antibody, CYSLT2 antibody, CYSLT2R antibody, HG57 antibody, HPN321 antibody, KPG_011 antibody, hGPCR21 antibody, 2300001H05Rik antibody, Cltr2 antibody, Cyslt2 antibody, cysLT2R antibody, cysteinyl leukotriene receptor 2 antibody, CYSLTR2 antibody, Cysltr2 antibody

Background: Cysteinyl leukotriene receptor 2 (CysLT2) is a Chemoattractant Receptor that binds neutrophil chemoattractants such as cysteinyl leukotrienes. These ligands have potent proinflammatory activity and are implicated in many features of asthma including edema, bronchial constriction, and hyperreactivity (Bisgaard et al., 2000). Activation of cysteinyl leukotriene receptor 2 induces cell contraction and/or relaxation.

Gene ID: 57105

UniProt: Q9NS75