CIB1 antibody (truncated)

Catalog No. ABIN2464036

Product Details anti-CIB1 Antibody

Target: CIB1 (Calcium and Integrin-Binding Protein 1 (CIB1))

Binding Specificity: truncated

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CIB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: Ni-NTA purified truncated recombinant CIB1 expressed in E. Coli strain BL21 (DE3).

Clone: 5A1F5E12-5A1H7E12

Application Details

Application Notes: Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: -20 °C

Storage Comment: CIB1 monoclonal antibody can be stored at -20 °C, stable for one year.

Target Details for CIB1

Target: CIB1 (Calcium and Integrin-Binding Protein 1 (CIB1))

Alternative Name: CIB1 (CIB1 Products)

Synonyms: zgc:112015 antibody, CIB antibody, CIBP antibody, KIP1 antibody, PRKDCIP antibody, SIP2-28 antibody, Cibkip antibody, Kip antibody, Prkdcip antibody, Cib antibody, Sip2-28 antibody, calcium and integrin binding 1 (calmyrin) antibody, calcium and integrin-binding protein 1 antibody, calcium and integrin binding 1 antibody, Calcium and integrin-binding protein 1 antibody, cib1 antibody, CpipJ_CPIJ003501 antibody, CIB1 antibody, kip1 antibody, Cib1 antibody

Background: CIB1(also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21 kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.

Gene ID: 10519

NCBI Accession: NP_001264693

UniProt: Q99828