FBXL16
Reactivity: Human
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 594
Application Notes
FBXL16 antibody can be used for detection of FBXL16 by ELISA at 1:62500. FBXL16 antibody can be used for detection of FBXL16 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handling Advice
As with any antibody avoid repeat freeze-thaw cycles.
Storage
4 °C/-20 °C
Storage Comment
For short periods of storage (days) store at 4 °C. For longer periods of storage, store FBXL16 antibody at -20 °C.
Target
FBXL16
(F-Box and Leucine-Rich Repeat Protein 16 (FBXL16))
C16orf22 antibody, Fbl16 antibody, c380A1.1 antibody, BC042620 antibody, Scirr1 antibody, VIER F-box proteine 2 antibody, F-box and leucine rich repeat protein 16 antibody, fbxl16, putative antibody, F-box and leucine-rich repeat protein 16 antibody, VIER F-box protein 2 antibody, FBXL16 antibody, Smp_174380 antibody, fbxl16 antibody, Fbxl16 antibody, VFB2 antibody
Background
FBXL16 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.Members of the F-box protein family, such as FBXL16, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).