NAGS antibody
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- Target See all NAGS Antibodies
- NAGS (N-Acetylglutamate Synthase (NAGS))
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Reactivity
- Human, Mouse, Rat, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NAGS antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NAGS.
- Top Product
- Discover our top product NAGS Primary Antibody
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- Application Notes
- NAGS antibody can be used for detection of NAGS by ELISA at 1:312500. NAGS antibody can be used for detection of NAGS by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store NAGS antibody at -20 °C.
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- Target
- NAGS (N-Acetylglutamate Synthase (NAGS))
- Alternative Name
- NAGS (NAGS Products)
- Synonyms
- VF0585 antibody, AGAS antibody, ARGA antibody, 1700120E20Rik antibody, argA antibody, RGD1565783 antibody, N-acetylglutamate synthase antibody, amino-acid acetyltransferase ArgA antibody, argA antibody, ECs3675 antibody, VP2371 antibody, Psyr_0254 antibody, Sde_0360 antibody, NAGS antibody, Nags antibody
- Background
- NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
- Molecular Weight
- 58 kDa
- Gene ID
- 162417
- NCBI Accession
- NP_694551
- UniProt
- Q8N159
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