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NAGS antibody

NAGS Reactivity: Human, Mouse, Rat, Dog WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2463410
  • Target See all NAGS Antibodies
    NAGS (N-Acetylglutamate Synthase (NAGS))
    Reactivity
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog
    Host
    • 8
    • 1
    Rabbit
    Clonality
    • 9
    Polyclonal
    Conjugate
    • 9
    This NAGS antibody is un-conjugated
    Application
    • 9
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by protein A chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NAGS.
    Top Product
    Discover our top product NAGS Primary Antibody
  • Application Notes
    NAGS antibody can be used for detection of NAGS by ELISA at 1:312500. NAGS antibody can be used for detection of NAGS by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store NAGS antibody at -20 °C.
  • Target
    NAGS (N-Acetylglutamate Synthase (NAGS))
    Alternative Name
    NAGS (NAGS Products)
    Synonyms
    VF0585 antibody, AGAS antibody, ARGA antibody, 1700120E20Rik antibody, argA antibody, RGD1565783 antibody, N-acetylglutamate synthase antibody, amino-acid acetyltransferase ArgA antibody, argA antibody, ECs3675 antibody, VP2371 antibody, Psyr_0254 antibody, Sde_0360 antibody, NAGS antibody, Nags antibody
    Background
    NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
    Molecular Weight
    58 kDa
    Gene ID
    162417
    NCBI Accession
    NP_694551
    UniProt
    Q8N159
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