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PRDM12 antibody

PRDM12 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2461913
  • Target See all PRDM12 Antibodies
    PRDM12 (PR Domain Containing 12 (PRDM12))
    Reactivity
    • 22
    • 17
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 20
    • 2
    Rabbit
    Clonality
    • 20
    • 2
    Polyclonal
    Conjugate
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRDM12 antibody is un-conjugated
    Application
    • 15
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by protein A chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PRDM12.
    Top Product
    Discover our top product PRDM12 Primary Antibody
  • Application Notes
    PRDM12 antibody can be used for detection of PRDM12 by ELISA at 1:62500. PRDM12 antibody can be used for detection of PRDM12 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store PRDM12 antibody at -20 °C.
  • Target
    PRDM12 (PR Domain Containing 12 (PRDM12))
    Alternative Name
    PRDM12 (PRDM12 Products)
    Synonyms
    PRDM12 antibody, prdm12 antibody, MGC146714 antibody, PFM9 antibody, pfm9 antibody, Gm998 antibody, PR/SET domain 12 antibody, PR domain containing 12 antibody, PR domain containing 12 L homeolog antibody, PR domain containing 12a antibody, PRDM12 antibody, prdm12 antibody, prdm12.L antibody, Prdm12 antibody, prdm12a antibody
    Background
    PRDM12 belongs to PR-domain family which are involved in human cancers in an unusual yin-yang fashion. Two products are normally produced from a PR-domain family member which differ by the presence or absence of the PR domain, the PR-plus product is disrupted or underexpressed whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, a result of either genetic or epigenetic events, appears to be an important cause of malignancy. PRDM12 may have a potential role in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion.
    Molecular Weight
    40 kDa
    Gene ID
    59335
    NCBI Accession
    NP_067632
    UniProt
    Q9H4Q4
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