NFIL3 antibody
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- Target See all NFIL3 Antibodies
- NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NFIL3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFIL3.
- Top Product
- Discover our top product NFIL3 Primary Antibody
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- Application Notes
- NFIL3 antibody can be used for detection of NFIL3 by ELISA at 1:312500. NFIL3 antibody can be used for detection of NFIL3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store NFIL3 antibody at -20 °C.
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- Target
- NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))
- Alternative Name
- NFIL3 (NFIL3 Products)
- Synonyms
- e4bp4 antibody, il3bp1 antibody, nfil3a antibody, nf-il3a antibody, MGC107826 antibody, NFIL3 antibody, E4BP4 antibody, IL3BP1 antibody, NF-IL3A antibody, NFIL3A antibody, E4BP4-1 antibody, zgc:100867 antibody, AV225605 antibody, nuclear factor, interleukin 3 regulated antibody, nuclear factor, interleukin 3 regulated L homeolog antibody, nuclear factor, interleukin 3, regulated antibody, nfil3 antibody, NFIL3 antibody, Nfil3 antibody, nfil3.L antibody
- Background
- NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
- Molecular Weight
- 51 kDa
- Gene ID
- 4783
- NCBI Accession
- NP_005375
- UniProt
- Q14211
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