SAP30 antibody
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- Target See all SAP30 Antibodies
- SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SAP30 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SAP30.
- Top Product
- Discover our top product SAP30 Primary Antibody
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- Application Notes
- SAP30 antibody can be used for detection of SAP30 by ELISA at 1:312500. SAP30 antibody can be used for detection of SAP30 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store SAP30 antibody at -20 °C.
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- Target
- SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))
- Alternative Name
- SAP30 (SAP30 Products)
- Synonyms
- 30kDa antibody, Sin3A associated protein 30 antibody, sin3 associated polypeptide antibody, Sin3A associated protein 30kDa S homeolog antibody, SAP30 antibody, Sap30 antibody, sap30.S antibody
- Background
- Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP30 is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3.
- Molecular Weight
- 23 kDa
- Gene ID
- 8819
- NCBI Accession
- NP_003855
- UniProt
- O75446
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