ZNF76 antibody

Catalog No. ABIN2461696

Product Details anti-ZNF76 Antibody

Target: ZNF76 (Zinc Finger Protein 76 (Expressed in Testis) (ZNF76))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF76 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZNF76.

Application Details

Application Notes: ZNF76 antibody can be used for detection of ZNF76 by ELISA at 1:312500. ZNF76 antibody can be used for detection of ZNF76 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ZNF76 antibody at -20 °C.

Target Details for ZNF76

Target: ZNF76 (Zinc Finger Protein 76 (Expressed in Testis) (ZNF76))

Alternative Name: ZNF76 (ZNF76 Products)

Synonyms: 2810027J07 antibody, BC025615 antibody, Znf76 antibody, D6S229E antibody, ZNF523 antibody, Zfp523 antibody, zinc finger protein 523 antibody, zinc finger protein 76 antibody, Zfp523 antibody, ZNF76 antibody

Background: ZNF76 belongs to the krueppel C2H2-type zinc-finger protein family. ZNF76 is a general transcription repressor targeting TATA-binding protein (TBP), through a process regulated by sumoylation. ZNF76 interacts with TBP through both its N and C termini, and both regions are required for ZNF76 to exert its inhibitory function on p53-mediated transactivation. As a TBP-interacting transcriptional modulator, ZNF76 is also regulated by alternative splicing.

Molecular Weight: 62 kDa

Gene ID: 7629

NCBI Accession: NP_003418

UniProt: P36508