DDX46 antibody

Catalog No. ABIN2461582

Product Details anti-DDX46 Antibody

Target: DDX46 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 46 (DDX46))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX46 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DDX46.

Application Details

Application Notes: DDX46 antibody can be used for detection of DDX46 by ELISA at 1:12500. DDX46 antibody can be used for detection of DDX46 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DDX46 antibody at -20 °C.

Target Details for DDX46

Target: DDX46 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 46 (DDX46))

Alternative Name: DDX46 (DDX46 Products)

Synonyms: MMI9.2 antibody, MMI9_2 antibody, RNA HELICASE antibody, fb39a03 antibody, fj67d06 antibody, wu:fb39a03 antibody, wu:fj67d06 antibody, PRPF5 antibody, Prp5 antibody, 2200005K02Rik antibody, 8430438J23Rik antibody, AI325430 antibody, AI957095 antibody, mKIAA0801 antibody, DEAD box RNA helicase (PRH75) antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 antibody, DEAD-box helicase 46 antibody, RNA helicase-like protein antibody, PRH75 antibody, ddx46 antibody, DDX46 antibody, Ddx46 antibody, TDRD12 antibody

Background: DDX46 is a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX46 is a component of the 17S U2 snRNP complex, it plays an important role in pre-mRNA splicing.

Molecular Weight: 113 kDa

Gene ID: 9879

NCBI Accession: NP_055644

UniProt: Q7L014