Mesp2 antibody

Catalog No. ABIN2461445

Product Details anti-Mesp2 Antibody

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mesp2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MESP2.

Application Details

Application Notes: MESP2 antibody can be used for detection of MESP2 by ELISA at 1:62500. MESP2 antibody can be used for detection of MESP2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MESP2 antibody at -20 °C.

Target Details for Mesp2

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Alternative Name: MESP2 (Mesp2 Products)

Synonyms: bHLHc6 antibody, SCDO2 antibody, mesoderm posterior 2 antibody, mesoderm posterior bHLH transcription factor 2 antibody, Mesp2 antibody, MESP2 antibody

Background: Somite boundaries formed during embryogenesis, at the interface between Notch1-activated and -repressed domains. Genetic and biochemical studies indicate that this interface is generated by suppression of Notch activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe gene (Lfng). It is proposed that the oscillation of Notch activity is arrested and translated in the wavefront by Mesp2.

Molecular Weight: 41 kDa

Gene ID: 17293

NCBI Accession: NP_032615

UniProt: O08574