CHMP3 antibody

Catalog No. ABIN2460955

Product Details anti-CHMP3 Antibody

Target: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human VPS24.

Application Details

Application Notes: VPS24 antibody can be used for detection of VPS24 by ELISA at 1:12500. VPS24 antibody can be used for detection of VPS24 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store VPS24 antibody at -20 °C.

Target Details for CHMP3

Target: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Alternative Name: VPS24 (CHMP3 Products)

Synonyms: CG9779 antibody, Dmel\\CG9779 antibody, Vps24 antibody, dvps24 antibody, vps24 antibody, VPS24 antibody, CHMP3 antibody, GB15107 antibody, wu:fb47g01 antibody, zgc:76972 antibody, NEDF antibody, 25.1 antibody, 4921505F14Rik antibody, 9130011K15Rik antibody, CGI-49 antibody, D6Ertd286e antibody, Vacuolar protein sorting 24 antibody, charged multivesicular body protein 3 antibody, SNF7 family protein antibody, hypothetical protein antibody, neuroendocrine differentiation factor, putative antibody, charged multivesicular body protein 3 S homeolog antibody, Vps24 antibody, chmp3 antibody, VPS24.2 antibody, CpipJ_CPIJ004098 antibody, PGTG_02107 antibody, LOC5569267 antibody, Smp_032150 antibody, CHMP3 antibody, LOC410607 antibody, Chmp3 antibody, chmp3.S antibody

Background: VPS24 encodes a protein that acts in the sorting of transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily.

Molecular Weight: 25 kDa

Gene ID: 51652

NCBI Accession: NP_057163

UniProt: Q3ZTS9