REXO4 antibody

Catalog No. ABIN2460618

Product Details anti-REXO4 Antibody

Target: REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))

Reactivity: Human, Rat, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REXO4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human REXO4.

Application Details

Application Notes: REXO4 antibody can be used for detection of REXO4 by ELISA at 1:1562500. REXO4 antibody can be used for detection of REXO4 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store REXO4 antibody at -20 °C.

Target Details for REXO4

Target: REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))

Alternative Name: REXO4 (REXO4 Products)

Synonyms: REXO4 antibody, REX4 antibody, XPMC2 antibody, XPMC2H antibody, Gm111 antibody, Xpmc2h antibody, xpmc2 antibody, im:7156740 antibody, si:ch73-209e20.4 antibody, REX4 homolog, 3'-5' exonuclease antibody, REX4, 3'-5' exonuclease antibody, RNA exonuclease 4 antibody, putative 3'-5' exonuclease antibody, REXO4 antibody, Rexo4 antibody, LOC100229203 antibody, rexo4.S antibody, CAALFM_C112440WA antibody, rexo4 antibody

Background: The regulation of the quinone reductase (QR) gene as well as other genes involved in detoxification is known to be mediated by an electrophile response element (EpRE). QR gene regulation by the antiestrogen-occupied estrogen receptor (ER) is mediated by the EpRE-containing region of the human QR gene, and the ER is one of the complex of proteins that binds to the EpRE. REXO4 directly binds to the EpRE and interacts with the ER. The activation of QR gene activity by REXO4 is enhanced in the presence of ER beta.

Molecular Weight: 47 kDa

Gene ID: 57109

NCBI Accession: NP_065118

UniProt: Q9GZR2