T-Box 19 antibody

Catalog No. ABIN2460436

Product Details anti-T-Box 19 Antibody

Target: T-Box 19 (TBX19)

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 19 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Antibody is supplied as total IgG.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TBX19.

Application Details

Application Notes: TBX19 antibody can be used for detection of TBX19 by ELISA at 1:62500. TBX19 antibody can be used for detection of TBX19 by western blot at 1.0-1.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 200 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TBX19 antibody at -20 °C.

Target Details for T-Box 19

Target: T-Box 19 (TBX19)

Alternative Name: TBX19 (TBX19 Products)

Synonyms: TBX19 antibody, TBS19 antibody, TPIT antibody, dJ747L4.1 antibody, CH-TBXT antibody, TBXT antibody, AU019250 antibody, D1Ertd754e antibody, Tpit antibody, T-box 19 antibody, TBX19 antibody, Tbx19 antibody

Background: TBX19 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX19 is the human ortholog of mouse Tbx19/Tpit gene. Studies in mouse show that Tpit protein is present only in the two pituitary pro-opiomelanocortin (POMC)-expressing lineages, the corticotrophs and melanotrophs. Mutations in the human ortholog were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage.

Molecular Weight: 48 kDa

Gene ID: 9095

NCBI Accession: NP_005140

UniProt: O60806