FBXO39 antibody

Catalog No. ABIN2459635

Product Details anti-FBXO39 Antibody

Target: FBXO39 (F-Box Protein 39 (FBXO39))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO39 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FBXO39.

Application Details

Application Notes: FBXO39 antibody can be used for detection of FBXO39 by ELISA at 1:1562500. FBXO39 antibody can be used for detection of FBXO39 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FBXO39 antibody at -20 °C.

Target Details for FBXO39

Target: FBXO39 (F-Box Protein 39 (FBXO39))

Alternative Name: FBXO39 (FBXO39 Products)

Synonyms: Fbx39 antibody, 1700010H23Rik antibody, F-box protein 39 antibody, FBXO39 antibody, Fbxo39 antibody

Background: FBXO39 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.Members of the F-box protein family, such as FBXO39, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).

Molecular Weight: 53 kDa

Gene ID: 162517

NCBI Accession: NP_694962

UniProt: Q8N4B4