GRPEL2 antibody

Catalog No. ABIN2459606

Product Details anti-GRPEL2 Antibody

Target: GRPEL2 (GrpE-Like 2, Mitochondrial (GRPEL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRPEL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GRPEL2.

Application Details

Application Notes: GRPEL2 antibody can be used for detection of GRPEL2 by ELISA at 1:312500. GRPEL2 antibody can be used for detection of GRPEL2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GRPEL2 antibody at -20 °C.

Target Details for GRPEL2

Target: GRPEL2 (GrpE-Like 2, Mitochondrial (GRPEL2))

Alternative Name: GRPEL2 (GRPEL2 Products)

Synonyms: mt-GrpE2 antibody, mt-Grpel2 antibody, Afap1l1 antibody, Mt-GrpE2 antibody, GrpE-like 2, mitochondrial antibody, GrpE like 2, mitochondrial antibody, Grpel2 antibody, GRPEL2 antibody

Background: GRPEL2 is an essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. GRPEL2 seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. GRPEL2 stimulates ATPase activity of mt-HSP70. GRPEL2 may also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.

Molecular Weight: 25 kDa

Gene ID: 134266

NCBI Accession: NP_689620

UniProt: Q8TAA5