XYLT2 antibody
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- Target See all XYLT2 Antibodies
- XYLT2 (Xylosyltransferase II (XYLT2))
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Reactivity
- Mouse, Human, Rat, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This XYLT2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human XYLT2.
- Top Product
- Discover our top product XYLT2 Primary Antibody
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- Application Notes
- XYLT2 antibody can be used for detection of XYLT2 by ELISA at 1:312500. XYLT2 antibody can be used for detection of XYLT2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store XYLT2 antibody at -20 °C.
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- Target
- XYLT2 (Xylosyltransferase II (XYLT2))
- Alternative Name
- XYLT2 (XYLT2 Products)
- Synonyms
- MGC89331 antibody, PXYLT2 antibody, XT-II antibody, XT2 antibody, xylT-II antibody, xt-II antibody, E030002B02Rik antibody, xylt-II antibody, xylosyltransferase II antibody, xylosyltransferase 2 antibody, xylt2 antibody, XYLT2 antibody, Xylt2 antibody
- Background
- XYLT2 is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- Molecular Weight
- 97 kDa
- Gene ID
- 64132
- NCBI Accession
- NP_071450
- UniProt
- Q9H1B5
- Pathways
- Glycosaminoglycan Metabolic Process
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