PSMC3IP antibody
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- Target See all PSMC3IP Antibodies
- PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))
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Reactivity
- Mouse, Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSMC3IP antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMC3IP.
- Top Product
- Discover our top product PSMC3IP Primary Antibody
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- Application Notes
- PSMC3IP antibody can be used for detection of PSMC3IP by ELISA at 1:1562500. PSMC3IP antibody can be used for detection of PSMC3IP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PSMC3IP antibody at -20 °C.
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- Target
- PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))
- Alternative Name
- PSMC3IP (PSMC3IP Products)
- Synonyms
- PSMC3IP antibody, Arabidopsis Hop2 homolog antibody, T6J4.9 antibody, T6J4_9 antibody, C79099 antibody, GT198 antibody, HOP2 antibody, Tbpip antibody, HUMGT198A antibody, ODG3 antibody, TBPIP antibody, Gt198 antibody, zgc:86785 antibody, PSMC3 interacting protein antibody, homologous-pairing protein 2 homolog antibody, Homologous-pairing protein 2 homolog antibody, homologous-pairing protein 2 homolog-like antibody, Tat-binding protein 1(Tbp-1)-interacting protein (TBPIP) antibody, proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein antibody, PSMC3 interacting protein L homeolog antibody, PSMC3IP antibody, LOC726449 antibody, LOC100165513 antibody, hop2 antibody, psmc3ip antibody, LOC100633854 antibody, LOC100650062 antibody, LOC789362 antibody, AHP2 antibody, Psmc3ip antibody, psmc3ip.L antibody
- Background
- PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.
- Molecular Weight
- 24 kDa
- Gene ID
- 29893
- NCBI Accession
- NP_037422
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