RDH16 antibody

Catalog No. ABIN2458627

Product Details anti-RDH16 Antibody

Target: RDH16 (Retinol Dehydrogenase 16 (All-Trans) (RDH16))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RDH16 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RDH16.

Application Details

Application Notes: RDH16 antibody can be used for detection of RDH16 by ELISA at 1:312500. RDH16 antibody can be used for detection of RDH16 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RDH16 antibody at -20 °C.

Target Details for RDH16

Target: RDH16 (Retinol Dehydrogenase 16 (All-Trans) (RDH16))

Alternative Name: RDH16 (RDH16 Products)

Synonyms: MGC68820 antibody, CRAD antibody, CRAD1 antibody, Rdh6 antibody, RODH-4 antibody, SDR9C8 antibody, Rdh2 antibody, RoDHII antibody, retinol dehydrogenase 16 (all-trans) L homeolog antibody, retinol dehydrogenase 16 (all-trans) antibody, retinol dehydrogenase 16 antibody, rdh16.L antibody, RDH16 antibody, rdh16 antibody, Rdh16 antibody

Background: RDH16 is an oxidoreductase with a preference for NAD. It oxidizes all-trans-retinol and 13-cis-retinol to the corresponding aldehydes. RDH16 has higher activity towards CRBP-bound retinol than with free retinol. It also oxidizes androstanediol and androsterone to dihydrotestosterone and androstanedione. RDH16 can also catalyze the reverse reaction.

Molecular Weight: 36 kDa

Gene ID: 8608

NCBI Accession: NP_003699

UniProt: O75452

Pathways: Steroid Hormone Biosynthesis