ZNF146
Reactivity: Human
IF (p), IF (cc)
Host: Rabbit
Polyclonal
AbBy Fluor® 594
Application Notes
ZNF146 antibody can be used for detection of ZNF146 by ELISA at 1:12500. ZNF146 antibody can be used for detection of ZNF146 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handling Advice
As with any antibody avoid repeat freeze-thaw cycles.
Storage
4 °C/-20 °C
Storage Comment
For short periods of storage (days) store at 4 °C. For longer periods of storage, store ZNF146 antibody at -20 °C.
ZNF146 (OZF) overexpression in tumours may alter the balance between hRap1 and other telomeric proteins, therefore OZF function may be linked to telomere regulation. ZNF146 is strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. ZNF146 is overexpresseed in 80 % of colorectal cancers.