CD248 antibody (full length)

Catalog No. ABIN2452152

Product Details anti-CD248 Antibody

Target: CD248 (CD248 Molecule, Endosialin (CD248))

Binding Specificity: full length

Reactivity: Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD248 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Characteristics: Rabbit polyclonal antibody affinity purified with the immunogen after adsorption of anti-GST antibody with GST-affinity column.

Purification: Affinity purified

Immunogen: GST-full length Tem1 fusion protein expressed in E. coli

Isotype: IgG

Application Details

Application Notes: 1) Western blotting: 1/250~1/500
2) Immunoprecipitation

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 1 mg/mL BSA as carrier, 0.09 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CD248

Target: CD248 (CD248 Molecule, Endosialin (CD248))

Alternative Name: Tem1 (CD248 Products)

Synonyms: CD164L1 antibody, TEM1 antibody, 2610111G01Rik antibody, AI842296 antibody, Cd164l1 antibody, Tem1 antibody, fb96b12 antibody, wu:fb96b12 antibody, zgc:162651 antibody, CD248 molecule antibody, CD248 antigen, endosialin antibody, CD248 molecule, endosialin a antibody, CD248 antibody, Cd248 antibody, cd248a antibody

Background: Background: Tem1 is a low-molecular-weight GTP-binding protein (GTPase) which is required for the termination of M phase in cell division. The defect of Tem1 was lethal, and the Tem1-defective cells were arrested at telophase with high H1-kinase activity, indicating that Tem1 is required to exit from M phase. The defect of Tem1 was suppressed by a high dose of cdc15, which encodes a protein kinase. Tem1 functions upstream of cdc15 kinase and may be required to activate the cdc15 protein kinase pathway. A cascade consisting of Tem1 and kinases act to terminate mitosis.