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Shugoshin antibody

SGOL1 Reactivity: Schizosaccharomyces pombe WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2452123
  • Target See all Shugoshin (SGOL1) Antibodies
    Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))
    Reactivity
    • 45
    • 5
    • 5
    • 1
    Schizosaccharomyces pombe
    Host
    • 42
    • 3
    Rabbit
    Clonality
    • 43
    • 2
    Polyclonal
    Conjugate
    • 24
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Shugoshin antibody is un-conjugated
    Application
    • 30
    • 27
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Purification
    Affinity purified
    Sterility
    Sterile filtered
    Top Product
    Discover our top product SGOL1 Primary Antibody
  • Application Notes
    1) Western blotting: 1,000 fold dilution
    2) Immunofluoresece staining: 100 fold dilution
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.2 mg/mL
    Buffer
    1 mg/mL BSA, PBS ( pH 7.2), 50 % glycerol
    Preservative
    Azide free
    Storage
    -20 °C
  • Yamagishi, Sakuno, Shimura, Watanabe: "Heterochromatin links to centromeric protection by recruiting shugoshin." in: Nature, Vol. 455, Issue 7210, pp. 251-5, (2008) (PubMed).

    Watanabe, Kitajima: "Shugoshin protects cohesin complexes at centromeres." in: Philosophical transactions of the Royal Society of London. Series B, Biological sciences, Vol. 360, Issue 1455, pp. 515-21, discussion 521, (2005) (PubMed).

    Kitajima, Kawashima, Watanabe: "The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis." in: Nature, Vol. 427, Issue 6974, pp. 510-7, (2004) (PubMed).

  • Target
    Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))
    Abstract
    SGOL1 Products
    Synonyms
    sgo1 antibody, NY-BR-85 antibody, SGO antibody, Sgo1 antibody, 3300001M08Rik antibody, C81037 antibody, shugoshin 1 antibody, shugoshin centromeric cohesion 1 antibody, shugoshin 1 L homeolog antibody, Sgo1 antibody, sgo1 antibody, sgo1.L antibody, SGO1 antibody
    Background
    Shugoshin 1 (Sgo1), a meiosis-specific protein, protects centromeric Rec8 from degradation during first meiotic division (meiosis I) in fission yeast Schizosaccharomyces pombe. This protein appears at late prophase of meiosis I and is degraded at anaphase I. Heterochromatin protein Swi6 associates directly with Sgo1. A point mutation of Sgo1 (V242E), which abolishes the interaction with Swi6, impairs the centromeric localization and function of Sgo1. The forced centromeric localization of Sgo1 restores proper meiotic chromosome segregation in swi6 cells. Using this antibody in Western blotting, the band of 37 kD was observed in wild type S. pombe MP111 extract.
    UniProt
    Q9P7A0
    Pathways
    Maintenance of Protein Location
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