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RRM2 antibody (C-Term)

RRM2 Reactivity: Human, Mouse, Rat, Xenopus laevis WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2452118
  • Target See all RRM2 Antibodies
    RRM2 (Ribonucleotide Reductase M2 (RRM2))
    Binding Specificity
    • 15
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 54
    • 13
    • 12
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Xenopus laevis
    Host
    • 49
    • 5
    Rabbit
    Clonality
    • 42
    • 12
    Polyclonal
    Conjugate
    • 22
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RRM2 antibody is un-conjugated
    Application
    • 37
    • 14
    • 13
    • 13
    • 8
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Cross-Reactivity (Details)
    Not tested in other species.
    Purification
    Affinity-purified with the immunogen peptide
    Sterility
    Sterile filtered
    Immunogen
    C-terminal peptide of Human and Mouse RRM2, C-TENSFTLDADF, conjugated with KLH
    Top Product
    Discover our top product RRM2 Primary Antibody
  • Application Notes
    1) Western blotting: ~ 1/1,000 dilution
    Not tested for other applications
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS (x1), 50 % glycerol. Azide and carrier free.
    Preservative
    Azide free
    Storage
    -20 °C
    Storage Comment
    Upon receipt aliquot and store at -20 C
  • Takada, Shibata, Hiraoka, Masuda: "Identification of ribonucleotide reductase protein R1 as an activator of microtubule nucleation in Xenopus egg mitotic extracts." in: Molecular biology of the cell, Vol. 11, Issue 12, pp. 4173-87, (2000) (PubMed).

  • Target
    RRM2 (Ribonucleotide Reductase M2 (RRM2))
    Alternative Name
    RRM2 / RNR-R2 (RRM2 Products)
    Synonyms
    R2 antibody, RR2 antibody, RR2M antibody, AA407299 antibody, rrm2 antibody, rr2m antibody, cb111 antibody, chunp6884 antibody, r2 antibody, ribonucleotide reductase regulatory subunit M2 antibody, ribonucleotide reductase M2 antibody, ribonucleotide reductase M2, gene 2 L homeolog antibody, ribonucleotide reductase M2, gene 1 antibody, ribonucleotide reductase M2 polypeptide antibody, RRM2 antibody, Rrm2 antibody, rrm2.2.L antibody, rrm2.1 antibody, rrm2 antibody
    Background
    Betag Ribonucleoside-diphosphate reductase subunit M2 (RRM2, 389 aa, 45 kDa) also known as ribonucleotide reductase subunit R2 (RNR-R2), is a rate-limiting subunit of an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides. Deoxyribonucleotides in turn are used in the synthesis of DNA. The reaction catalyzed by RNR is strictly conserved in all living organisms. Furthermore RNR plays a critical role in regulating the total rate of DNA synthesis so that DNA to cell mass is maintained at a constant ratio during cell division and DNA repair.
    UniProt
    P31350
    Pathways
    Mitotic G1-G1/S Phases
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