RAD21 antibody (C-Term)

Catalog No. ABIN2452087

Product Details anti-RAD21 Antibody

Target: RAD21 (RAD21 Homolog (RAD21))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD21 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity purified with immunogen peptide from rabbit serum of immunized rabbit

Sterility: Sterile filtered

Immunogen: Human Rad21 C-terminal peptide, C-ATPGPRFHII

Application Details

Application Notes: 1) Western blotting: 1/2,000 dilution
2) Immunofluorescence staining: 1/100~1/500 dilution

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS (x1), 50 % glycerol. Azide and carrier free.

Preservative: Azide free

Storage: -20 °C

Storage Comment: Upon arrival centrifuge briefly and store at -20 C.

References for anti-RAD21 antibody (ABIN2452087)

Barton, Pearse, Marks: "Derivation of a dysplasia index for epidermal neoplasia." in: Dermatology (Basel, Switzerland), Vol. 185, Issue 3, pp. 190-5, (1992) (PubMed).

Target Details for RAD21

Target: RAD21 (RAD21 Homolog (RAD21))

Alternative Name: Rad21 (RAD21 Products)

Background: Rad21 (631 aa, 71 kDa) 2) is a cleavable component of cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate.

UniProt: O60216

Pathways: Positive Regulation of Endopeptidase Activity