KPNA4 antibody (full length)
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- Target See all KPNA4 Antibodies
- KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))
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Binding Specificity
- full length
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This KPNA4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- Reactive with human, simian, mouse, rat, hamster, canine and bovine importin a3. This antibody doesn't recognize other importin a family including a4.
- Characteristics
- The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by proprietary chromatography processes.
- Purification
- Purified
- Sterility
- Sterile filtered
- Immunogen
- Recombinant mouse importin a3 /KPNA4/ Qip 1 (full length)
- Clone
- 3D10
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product KPNA4 Primary Antibody
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- Application Notes
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1. Western blotting: 250~500 fold dilution
2. ELISA
This antibody doesn't work for immunostaining and immunoprecipitation. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, 50 % glycerol
- Preservative
- Azide free
- Storage
- -20 °C/-80 °C
- Storage Comment
- -20 C (For long term storage: -70 C)
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Triggering neural differentiation of ES cells by subtype switching of importin-alpha." in: Nature cell biology, Vol. 9, Issue 1, pp. 72-9, (2007) (PubMed).
: "Nucleocytoplasmic protein traffic and its significance to cell function." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 5, Issue 10, pp. 777-87, (2000) (PubMed).
: "Differential modes of nuclear localization signal (NLS) recognition by three distinct classes of NLS receptors." in: The Journal of biological chemistry, Vol. 272, Issue 42, pp. 26375-81, (1997) (PubMed).
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Triggering neural differentiation of ES cells by subtype switching of importin-alpha." in: Nature cell biology, Vol. 9, Issue 1, pp. 72-9, (2007) (PubMed).
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- Target
- KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))
- Alternative Name
- Importin alpha 3 / Qip1KPNA4 (KPNA4 Products)
- Background
- Importin a proteins play a pivotal role in the import of proteins from the cytoplasm to the nucleus. Importin a proteins shuttle between nucleus and cytoplasm, bind nuclear localization signal (NLS)-bearing proteins, and mediate the protein import into the nucleus with importin b. Several importin a isotypes have been identified, each exhibiting differential recognition and nuclear transport, probably via preferential binding to a particular NLS. The importin a3 (KPNA4, Qip1) is a member of the importin a family of proteins belonging to the Qip1 subfamily.
- Pathways
- Protein targeting to Nucleus
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