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KPNA4 antibody (full length)

KPNA4 Reactivity: Mouse WB, ELISA Host: Rat Monoclonal 3D10 unconjugated
Catalog No. ABIN2452037
  • Target See all KPNA4 Antibodies
    KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))
    Binding Specificity
    • 15
    • 7
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    full length
    Reactivity
    • 41
    • 37
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Mouse
    Host
    • 51
    • 1
    Rat
    Clonality
    • 52
    Monoclonal
    Conjugate
    • 22
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KPNA4 antibody is un-conjugated
    Application
    • 39
    • 19
    • 14
    • 13
    • 11
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificity
    Reactive with human, simian, mouse, rat, hamster, canine and bovine importin a3. This antibody doesn't recognize other importin a family including a4.
    Characteristics
    The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by proprietary chromatography processes.
    Purification
    Purified
    Sterility
    Sterile filtered
    Immunogen
    Recombinant mouse importin a3 /KPNA4/ Qip 1 (full length)
    Clone
    3D10
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product KPNA4 Primary Antibody
  • Application Notes
    1. Western blotting: 250~500 fold dilution
    2. ELISA
    This antibody doesn't work for immunostaining and immunoprecipitation.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol
    Preservative
    Azide free
    Storage
    -20 °C/-80 °C
    Storage Comment
    -20 C (For long term storage: -70 C)
  • Yasuhara, Shibazaki, Tanaka, Nagai, Kamikawa, Oe, Asally, Kamachi, Kondoh, Yoneda: "Triggering neural differentiation of ES cells by subtype switching of importin-alpha." in: Nature cell biology, Vol. 9, Issue 1, pp. 72-9, (2007) (PubMed).

    Yoneda: "Nucleocytoplasmic protein traffic and its significance to cell function." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 5, Issue 10, pp. 777-87, (2000) (PubMed).

    Miyamoto, Imamoto, Sekimoto, Tachibana, Seki, Tada, Enomoto, Yoneda: "Differential modes of nuclear localization signal (NLS) recognition by three distinct classes of NLS receptors." in: The Journal of biological chemistry, Vol. 272, Issue 42, pp. 26375-81, (1997) (PubMed).

  • Target
    KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))
    Alternative Name
    Importin alpha 3 / Qip1KPNA4 (KPNA4 Products)
    Synonyms
    IPOA3 antibody, QIP1 antibody, SRP3 antibody, 6 antibody, ATIMPALPHA3 antibody, IMPA-3 antibody, IMPORTIN ALPHA 3 antibody, IMPORTIN ALPHA ISOFORM 3 antibody, MODIFIER OF SNC1 antibody, T10M13.16 antibody, T10M13_16 antibody, LOC100224013 antibody, 1110058D08Rik antibody, importin antibody, ipoa3 antibody, qip1 antibody, srp3 antibody, impa3 antibody, wu:fa56d07 antibody, wu:fa66g10 antibody, wu:fe14c04 antibody, wu:fi04h11 antibody, wu:fi19b05 antibody, karyopherin subunit alpha 4 antibody, ARM repeat superfamily protein antibody, importin alpha 3 antibody, karyopherin (importin) alpha 4 antibody, karyopherin alpha 4 (importin alpha 3) S homeolog antibody, karyopherin alpha 4 (importin alpha 3) antibody, KPNA4 antibody, MOS6 antibody, LOC100533341 antibody, Kpna4 antibody, kpna4.S antibody, kpna4 antibody
    Background
    Importin a proteins play a pivotal role in the import of proteins from the cytoplasm to the nucleus. Importin a proteins shuttle between nucleus and cytoplasm, bind nuclear localization signal (NLS)-bearing proteins, and mediate the protein import into the nucleus with importin b. Several importin a isotypes have been identified, each exhibiting differential recognition and nuclear transport, probably via preferential binding to a particular NLS. The importin a3 (KPNA4, Qip1) is a member of the importin a family of proteins belonging to the Qip1 subfamily.
    Pathways
    Protein targeting to Nucleus
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