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PARP1 antibody
PARP1
Reactivity: Human, Mouse, Rat
WB, ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PARP1 Antibody
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Target
See all PARP1 Antibodies
PARP1
(Poly (ADP-Ribose) Polymerase 1 (PARP1))
Reactivity
All reactivities for PARP1 antibodies
Human, Mouse, Rat
Host
All hosts for PARP1 antibodies
Rabbit
Clonality
All clonalities for PARP1 antibodies
Polyclonal
Conjugate
All conjugates for PARP1 antibodies
This PARP1 antibody is un-conjugated
Application
All applications for PARP1 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Purification
Affinity purification
Immunogen
Synthetic peptide of human PARP1
Isotype
IgG
Top Product
Discover our top product PARP1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB 1:500-1:2000, IHC 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.2 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Handling Advice
Avoid freeze / thaw cycles.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for PARP1
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Target
PARP1
(Poly (ADP-Ribose) Polymerase 1 (PARP1))
Alternative Name
PARP1 (PARP1 Products )
Synonyms
ADPRT antibody, ADPRT 1 antibody, ADPRT1 antibody, ARTD1 antibody, PARP antibody, PARP-1 antibody, PPOL antibody, pADPRT-1 antibody, Adprt antibody, Parp-1 antibody, 5830444G22Rik antibody, AI893648 antibody, Adprp antibody, Adprt1 antibody, C80510 antibody, parp-1 antibody, sPARP-1 antibody, BEST:LD21673 antibody, CG17685 antibody, CG17696 antibody, CG17718 antibody, CG40411 antibody, D.PARP antibody, Dm.pARTa antibody, Dmel\\CG40411 antibody, LD21673.3prime antibody, PARP1 antibody, dPARP antibody, parp antibody, adprt1 antibody, padprt-1 antibody, ppol antibody, si:dkey-206f10.3 antibody, wu:fc60f12 antibody, zgc:110092 antibody, poly(ADP-ribose) polymerase 1 antibody, poly (ADP-ribose) polymerase 1 antibody, poly (ADP-ribose) polymerase family, member 1 antibody, Poly-(ADP-ribose) polymerase antibody, poly(ADP-ribose) polymerase 1 L homeolog antibody, PARP1 antibody, Parp1 antibody, Parp antibody, parp1.L antibody, parp1 antibody
Background
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Molecular Weight
Calculated MW: 113 kDa
NCBI Accession
NP_001609
Pathways
Apoptosis , Caspase Cascade in Apoptosis , DNA Damage Repair , Production of Molecular Mediator of Immune Response , Maintenance of Protein Location
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